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Effect of deuteration on polymorph stability



I am wondering if anyone has observed a instance in which a molecule and
a partially deuterated form of that molecule preferentially crystallize
as different polymorphs.  In my specific case, it is a
dimethylphenanthrene; one form has two CH3 groups, the other CH3 and
CD3, and they appear as different polymorphs.  For the deuterated case,
Z' = 2, whereas for the undeuterated case Z' = 1, when crystallized
under as nearly identical conditions as I can produce.

Arnie Rheingold
U of Cal - San Diego
[EMAIL PROTECTED]




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