Re: The SSRI Withdrawal/SSRI-induced Manic Depression (Bipolar) Theory

In article<[EMAIL PROTECTED]>,
Scatterbrain <[EMAIL PROTECTED]> writes:
>The SSRI Withdrawal/SSRI-induced Manic Depressive (Bipolar) Syndrome 
>Theory 

 This article contains all sorts of dodgy statements.  It is a very
 dodgy idea to equate bipolar depression whose essence is a REPEATING
 swing with something which gives you a single up-then-down which
 never repeats.  MDMA is methyl dimethoxy amphetamine, most SSRIs
 are phenyl-alkyl amines with a longish chain, a further phenyl 
 ring with a strongly electronegative (usually fluorine) substituent
 dependent early on the chain.  They are not chemically THAT like
 each other.  The great majority of psychoactive drugs are anyway a
 single phenyl ring, phenyl extended to indole, or two bridged
 phenyl rings, plus an alkylamine chain: they're all much of a muchness.  
 
 SSRIs do not just "make people happy", if that's what you think
 then you know nothing.  Roughly speaking, by inducing more serotonin,
 they somehow unjam receptors which produce an anti-calming and
 anti-sleep effect, releasing the normal pro-calming and pro-sleep
 effect, and also relieving the downward pressure on noradrenaline 
 and dopamine so that the reduction in physical and mental activity
 clears up.  Where such problems are not present SSRIs will not
 have benefits on mood, although there is some evidence they
 make you more tough-minded and resolute.  Clear so far?  
 I think you've wandered off course a bit generally.


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