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Re: liver fibrosis / alcohol / iron



"doe" <[EMAIL PROTECTED]> wrote in message
news:[EMAIL PROTECTED]
> Alcohol. 2003 Jun;30(2):121-9.  Related Articles, Links
>
>
> Iron-induced oxidant stress in alcoholic liver fibrogenesis.
>
> Pietrangelo A.
>
> Centre for the Study of Iron Disorders, Department of Internal Medicine,
> University of Modena and Reggio Emilia, Policlinico, Via del Pozzo 71,
41100,
> Modena, Italy
>
> Iron is an essential micronutrient.

!!!!!!!!!!!!!!!!!!!!!!!

>However, because human beings have no means
> to control iron excretion, excess iron, regardless of the route of entry,
> accumulates in parenchymal organs and threatens cell viability. Indeed,
when
> iron-buffering capability is overwhelmed,

The operative word is WHEN.

>At the molecular level, the presence of catalytically active
> "free iron" may (1) contribute directly to the hepatotoxicity of alcohol

So, you are saying that alcohol alone is not bad for you, but it's the iron
that makes it poisonous ?







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