Re: near iron deficiency / hepatitis

>Subject: Re: near iron deficiency / hepatitis
>From: [EMAIL PROTECTED]  (doe)
>Date: 9/1/2003 12:53 PM Mountain Daylight Time
>Message-id: <[EMAIL PROTECTED]>
>
>>Subject: Re: near iron deficiency / hepatitis
>>From: "Manky Badger" [EMAIL PROTECTED] 
>>Date: 9/1/2003 8:23 AM Mountain Daylight Time
>>Message-id: <[EMAIL PROTECTED]>
>>
>>
>>"doe" <[EMAIL PROTECTED]> wrote in message
>>news:[EMAIL PROTECTED]
>>> >Subject: Re: near iron deficiency / hepatitis
>>> >From: "Manky Badger" [EMAIL PROTECTED]
>>> >Date: 8/31/2003 7:51 AM Mountain Daylight Time
>>
>>> >Would you advocate a meat diet ?
>>>
>>> I believe you already know the answer to that one ..
>>>
>>> >Would you recommend a vegetarian diet ?
>>>
>>> I believe you already know the answer to that one .
>>
>>Then why not abandon the sarcasm & ebter into the spirit of discuusion by
>>giving a clear, supported answer.
>>
>>>
>>> >Or is it that you don't know that there are certain foods which despite
>>> >being high in iron content contain other substances that prevent iron
>>> >absorbtion ?
>>>
>>> a-b-s-o-r-P-t-i-o-n
>>>
>>> If you require iron their ain't no oxalate in the world which is going to
>>> prevent your body from absorbing .. it ..
>>
>>Really - this would contradict most current theories.
>
>PLENTY of studies which confirm the above ..
>
>When one uses ARTIFICIALLY high markers to assess 'anemia' .. then chances
>are
>you are going to get ARTIFICIALLY high numbers of people considered to be ..
>anemic.
>
>"All those anemic vegetarians.. "
>
>http://www.llu.edu/llu/vegetarian/iron.htm
>

This study shows even though these people aren't considered to be iron
overloaded ACCORDING TO PARAMETERS SET BY THE MEDICAL PROFESSION .. the
reduction of the iron levels led to a 40% drop ..

So logic would say ..something ain't right in Denmark ..


1: Gastroenterology 2002 Apr;122(4):931-9 Related Articles, Links  


Effect of iron depletion in carbohydrate-intolerant patients with clinical
evidence of nonalcoholic fatty liver disease.

Facchini FS, Hua NW, Stoohs RA.

Department of Medicine, University of California San Francisco and San
Francisco General Hospital, San Francisco, California, USA. [EMAIL PROTECTED]

BACKGROUND & AIMS: Increased body iron, genetic hemochromatosis (GH) mutations,
and nonalcoholic fatty liver disease (NAFLD) tend to cluster in
carbohydrate-intolerant patients. In an attempt to further clarify the
interrelationships among these conditions, we studied 42
carbohydrate-intolerant patients who were free of the common GH mutations C282Y
and H63D, and had a serum iron saturation lower than 50%. METHODS: We measured
body iron stores, and induced iron depletion to a level of near-iron deficiency
(NID) by quantitative phlebotomy. RESULTS: In the 17 patients with clinical
evidence of NAFLD, we could not demonstrate supranormal levels of body iron
(1.6 +/- 0.2 vs. 1.4 +/- 0.2 g; P = 0.06). However, at NID, there was a 40%-55%
improvement (P = 0.05-0.0001) of both fasting and glucose-stimulated plasma
insulin concentrations, and near-normalization of serum alanine
aminotransferase activity (from 61 +/- 5 to 32 +/- 2 IU/L; P < 0.001).
CONCLUSIONS: These results reflect the insulin-sparing effect of iron depletion
and indicate a key role of iron and hyperinsulinemia in the pathogenesis of
NAFLD.

PMID: 11910345 [PubMed - indexed for MEDLINE] 

---------------------------------------------------

Another study found by lowering iron levels into the state COMMONLY FOUND IN
PREMENOPAUSAL WOMEN .. led to dramatic improvement ... again showing therefore
.. the 'state' commonly found in premenopausal women .. might not be all that
bad .. ?

I suppose since almost 20% of premenopausal women are considered to be anemic
.. then maybe the marker used to diagnose 'anemia' in women is actually set too
high ..

<<snip>>
Thus, although individuals
at high risk for ASCVD are not Fe-overloaded, they seem to benefit,
metabolically and hemodynamically, from lowering of body Fe to levels commonly
seen in premenopausal females.
<<snip>>

Ann N Y Acad Sci 2002 Jun;967:342-351 



Effect of Iron Depletion on Cardiovascular Risk Factors: Studies in
Carbohydrate-Intolerant Patients.

Facchini FS, Saylor KL
Department of Medicine, Division of Nephrology, San Francisco General Hospital
and University of California, San Francisco, California, USA. 

[Record supplied by publisher]


Controversy surrounds the role of iron (Fe) in atherosclerosis (ASCVD), mainly
due to the inaccuracy of assessing body Fe stores with serum ferritin and
transferrin saturation. Quantitative phlebotomy was used to test whether or not
(a) Fe stores are increased in individuals at high risk for ASCVD and (b) Fe
depletion to near-deficiency (NID) levels is associated with reduction of risk
factors for ASCVD. Thirty-one carbohydrate-intolerant subjects completed the
study. Fe stores were within normal limits (1.5 +/- 0.1 g). At NID, a
significant increase of HDL-cholesterol (p < 0.001) and reductions of blood
pressure (p < 0.001), total and LDL-cholesterol (p < 0.001), triglyceride (p <
0.001), fibrinogen (p < 0.001) and glucose and insulin responses to oral
glucose loading (p < 0.001) were noted, while homocysteine plasma concentration
remained unchanged. These effects were largely reversed by a 6-month period of
Fe repletion with reinstitution of Fe sufficiency. Thus, although individuals
at high risk for ASCVD are not Fe-overloaded, they seem to benefit,
metabolically and hemodynamically, from lowering of body Fe to levels commonly
seen in premenopausal females. 

PMID: 12079862 

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Who loves ya.
Tom


Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore
DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking