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This feature article published in Scientific American gives a good deal of information about our disease. It covers the actual mechanisms of Osteoporosis as well as the history and future of treatments. It explains the apparent paradox concerning Parathyroid Hormone (PTH) where elevated levels cause bone thinning yet it is what the bone builder Forteo is based on. The article also addresses the role of Insulin-like Growth Factor (IGF-1) It was written by Dr. Clifford J Rosen who is President of the American Society for Bone and Mineral Research and has written several leading textbooks on osteoporosis and bone health. He is also executive director of the Maine Center for Osteoporosis Research and Education in Bangor, Me., and is adjunct staff scientist at the Jackson Laboratory in Bar Harbor, Me. He has been associate clinical professor at Boston University Medical Center since 1993. The article is here: <http://tinyurl.com/w7c8> Or if you prefer actual URL: <http://www.sciam.com/article.cfm?articleID=000E5452-A1AB-1E41-89E0809EC 588EEDF&catID=2> HTH Tom
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