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Robert Myers <[EMAIL PROTECTED]> wrote: >[...] >Messianic or not, humble or not, I'm standing by my position: spending >money on monsters like Blue Gene is a waste. It won't make any real >progress on the problem it purports to be aiming at (I'm repeating >myself), and it would be *much* better to have tossed a few of those >boxes out to universities and let them figure out how to cope with a >few thousand of what Rupert refers to as mice, rather than putting >65000+ of them together to see what comes of it, other than a >meaningless Linpack score. I don't get this. You're pissed off because the notional declassified cover use is inefficient, not unproductive but inefficient? One, there are clear national security reasons to be building boxes like this, as has been repeatedly pointed out. Sufficiently accurate simulations of nuclear weapons to avoid the need for testing, simulations that can include defects and aging effects and the like, are a very important national priority. Two, boxes like this can do other types of work than protein folding, in terms of FEM and fluid flows and weather analysis and all sorts of other useful and neat things. Bigger boxes can do it more accurately, or faster, or both. Protein stuff was not the only reason to build them. Protein stuff is funding, both commercially and in research/academic environments, some large computing facilities. The people doing that work are finding computational proteomics to be a field that is extremely valuable to advancing theoretical research and commerce. They are finding it to be an enabling technology even though it's stuck with using obviously inefficient algorithms at this time. Systems like Blue Gene will work just as well at brute-forcing the protein folding and related problems as smaller systems are at this time. You seem to be offended that we're attacking the problem by brute force rather than finesse. That's fine, as far as it goes. Finesse is always useful. But finesse requires someone having finessed the problem so we can do it the better way already. But your value judgement of the low value of brute-forcing the problem is not matched by the demonstrated academic, research, and commercial user base's experience. I repeat: Experience. They are not buying systems to have labs full of cool blinkie lights. They're doing their work with it, producing papers and products. I was involved in building and supporting one commercial computational biology project, and did proposals for two others in the hundreds of nodes range, not world-class by current standards but large. A noticable fraction of the workdays of the researchers are being spent waiting for computational results to come back. While spending tens or hundreds of millions of dollars didn't make sense for any of these customers, there are projects going on in the field that will justify the use of systems of the scale of Blue Gene. That we theoretically should do much better eventually once we figure out how to finesse the algorithms is of no import to the calculation of current value of doing current computational projects in those fields. If it is worth doing now, with today's technology and algorithms, then it will be done. And it's being done. If there is money to be made now, and science and academic careers to be advanced now, using today's technology and algorithms, why on earth should people delay working on the problems with today's solutions just because we know that eventually, hopefully, we'll be able to do it so much better and faster? -george william herbert [EMAIL PROTECTED]
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